The Lions got jobbed AND despite that fact they still had plenty of chances to win the game. It isn't one or the other.
When the Pats get hosed by the refs like that I choose not to focus on the officials because the bottom line for me as a fan of my own team is that in almost every single case there is something they could have done to overcome the bad call. So I personally choose not to focus on the refs because is it wasted energy and frustration. Plus, if you go to an opposing team's message board in the wake of a loss to the Pats there is always (and I mean always, like, 100% of the time, no hyperbole) a thread about how the refs screwed the other team. It is the common mantra of loser fans everywhere, so when it comes to the Pats again I just personally choose not to engage in that kind of discussion, YMMV.
In this case because I don't care (actually pretty intensely dislike both teams), I have no issues spending some time discussing the horrendous way that the officials screwed the Lions. Engaging in that discussion does not negate the fact that the Lions still could have, and maybe should have, made enough plays to win the game. But the circumstances around the call in this case were so bad that I think as a fan of the NFL it warrants discussion.
I do think that the NFL needs to make pass interference something that can be reviewed, though. If it were common practice to take a second look at a PI call and in some cases reverse the call on the field it would have taken some of the sting out of this situation where the flag was thrown, the call was made, and then it was inexplicably reversed. You see much, much more marginal PI calls in almost every NFL game that are not reversed despite replays being shown on giant jumbotrons to the whole stadium. I just don't understand why in this particular case, in such a key situation, the officials on the field would deviate so substantially from normal protocol.