I think this is fair to a degree but the criticism can be more intelligent than that. For instance, Isaiah Wynn is a good player who had a bad game yesterday (maybe because he's banged up?). As you note, you can reduce that to a "Bill the GM" issue because Belichick picked Wynn, but since Wynn has largely been really good, that's an unreasonable criticism.
The two sacks that Wynn didn't let up yesterday were cases where the TE initially blocked a guy, then released, only to see the player the TE initially blocked get Cam. That strikes me as more of a coaching issue than a personnel issue; whether that's on Cam or on the TEs, they're not on the same page with what's going on there.
OTOH, this team has zero ability to generate explosive plays. You could single out, say, N'Keal Harry and his paltry 9.0 yards per catch on his career, or the RBs for a long run of 7 yards on 15 or so carries. Or you could look at how this team is generally built and conclude, reasonably, that this is a "Bill the GM" problem.
The offense cannot pick up chunk plays, so they really need to avoid negative plays. But they had three turnovers yesterday, and four sacks and a bad snap that all led to punts. That's eight drive-killing negative plays on 10 drives.
This is completely fair, and it is definitely apparent both yesterday and over five games that the Pats offense has almost no margin for error in terms of penalties, negative plays, and turnovers, and needs to string together 10 plus play drives to score touchdowns when they get long fields. When they are in second and 10 plus or third and 8 plus, for example, they are flat out not going to get it done. I think Byrd is actually fine as a receiving option, but he should be your third or fourth guy, not your top option.
The lack of production from Edelman and Harry is a huge issue. I actually take bigger issue with their lack of a replacement for Edelman given the criticality of the slot receiver to what they do. He looks terrible and yet no other receiver has made a push to take his snaps. As well as they transitioned from Brown to Welker and then to Welker to Edelman, they appear to be botching the next transition to a successor slot receiver. They reportedly tried to get Humphries a few years ago, but Tennessee beat them out, and unless you squint hard at Gunner there doesn’t seem to be an in house solution at that spot.
With Harry, it is increasingly unlikely he becomes a really good player as we progress through this season, even if he becomes a serviceable one. He just doesn’t catch the ball much past 5-10 yards, with a ton of touches occurring near the LOS itself. That isn’t necessarily terrible if he was doing damage with YAC (after all Deebo isn’t running Davante Adams’ route tree), but that skill hasn’t been as-advertised either. I don’t feel the apparent rage that some do about this pick, but I do think we are likely to see them on the hunt yet again for top receiving ability this offseason. All it takes is an acquisition or two at that position to make a real difference, but it isn’t like good receiving talent is hanging off trees, either.
I do think the OL being in relative shambles was a far bigger issue in yesterday’s loss (after all, how much did Davante Adams matter for GB yesterday when they got whipped upfront?), and ironically two of the biggest missed opportunities were misfires by Cam to open receivers (Byrd and Harry), but on a series to series basis their lack of a reliable shot play threat(s) certainly exacerbated their issues. I just don’t think yesterday was a good case study for it.