This is not the answer that you -- or anyone else -- is seeking, but here's one example from the distant past. In the 1960s and 1970s, a computer programming language named APL chose to use mathematical operators for the bulk of its grammar. Not just simple signs such as "+" and "-", but a large number of symbols that were, well, rather strange. For example, one symbol was the Greek letter capital Delta, which could be created in many cases by pressing a single key. But there were also symbols which looked like the capital Delta with a vertical or horizontal line drawn through it. One way to input these symbols was to type the character for Delta, then backspace, and then type a second character for the vertical line, overstriking the Delta.
For a period of time, that was the preferred method of writing code in APL on many terminals ...