Given the injury probability and history of 7'3+ guys in the league, I think they need to consider their window of contention to begin next year, and be open for maybe 5-6 years. As skinny and agile as he is, it's easy for me to armchair-doctor it and say that Wemby doesn't look like a guy whose knee (or poor heart) aches with every step he takes. But with every move he makes, I kinda hold my breath a little. We ran through the historical comps in his draft thread, but Shawn Bradley is basically the patron saint of having a full career in the NBA at that height. He played in 848 games, in at least part of 12 seasons, but only averaged >30' / game in one season (age 24) and was done as a rotation player at 28 (~1000' per year in the 4 seasons thereafter). Everyone else was moderately to substantially worse off than Bradley, career-wise. Wemby's skills will mean he starts and plays max minutes if he's healthy, but it's entirely possible that he won't last as an impact player beyond 28, or that 28 is a median expectation, anyway.
If so, the Spurs need to accelerate their turning of draft picks and assets into roster value. Trade a future Atlanta pick for a maybe-slightly-worse pick earlier. Take on some bad contracts this year or even next to get more assets, but whatever they do, draft guys who project to have quick impact. If they wait to draft another future star till (say) 2027 and he doesn't become a proper star until 2030, they may have wasted the Wembanyama Window by that point.