moondog80 said:
I don't mean to dismiss the seriousness of concussions, but for comparative purposes, does anyone know the prevalence of CTEs in the general population (i.e., people without a history of concussions)? I Googled it and came up empty.
I made a longer post in the football forum a little while ago, so I won't repost it all here. But your post hints at an important issue with all of this CTE research and all of the recent diagnoses.
These tests for "CTE" are not quite as ironclad as the media, and doctors who coined the term, would like you to think (this is coming from a BU School of Medicine alum who is plenty happy with all the recent BU publicity).
These post mortum brain biopsies and pathologic stains are testing for the most common abnormal protein that exists in the brain. It's the final common pathway for just about anything that goes wrong. Ryan Freel had "Grade 2 Abnormal Brain". The location of the abnormalies within the brain can be suggestive, but I havent seen anything definitive.
Now for a young guy who had a bunch of concussions, it's quite possible (probable?) that his brain wasn't normal because he took a bunch of hits. But the test didn't prove that. There needs to be a lot more study about how common this protein is in the general population, and at what ages it typically increases (we know the elderly, especially those with Alzheimers have a ton), and all of the the other causes.
I don't mean to dismiss CTE at all. It's very real, and we've known this for decades that boxing causes long term brain damage in a certain percentage of people. The most severe forms in people who have been beating each others heads in are pretty obvious.
But it's a little dicier when you start assuming every nonspecific neuro problem that happens all the time (forgetfulness, depression, anxiety, etc), is automatically, or even likely, linked to a traumatic brain injury. The science isn't close to there yet. And these pathologic stains "proving" CTE are still pretty crude.