I have no idea about the actual cases, so if there's extenuating circumstances, my apologies. That said,
Kevin Spacey comes to mind. He was considered one of the best actors of his generation, and he's been completely wiped off the face of the earth.
We can all agree being innocent in a court of law does not mean sexual assault didn't transpire. With that caveat, it's hard to find any other method of someone being vindicated of claims other than being found innocent.
Maybe he gets found guilty in a civil trial, I really don't know the details of Spaceys situation. That said, despite being found innocent on all charges filed by four accusers, Spacey's career is over and he has, unequivocally, been canceled.