All times ET. Lines from ESPN. Not all games listed.
Friday, September 6
7:00 PM BYU at SMU (-10.5), ESPN2
7:00 PM Western Illinois at Indiana, BTN
9:00 PM Duke at Northwestern (-2.5), FS1
Saturday, September 7
12:00 PM #3 Texas (-7.5) at #10 Michigan, FOX
12:00 PM Arkansas at #16 Oklahoma State (-7.5), ABC
12:00 PM #17 Kansas State (-10) at Tulane, ESPN
12:00 PM Pitt at Cincinnati (-2), ESPN2
12:00 PM #23 Georgia Tech (-3) at Syracuse, ACCN
12:00 PM Bowling Green at #8 Penn State (-34.5), BTN
12:00 PM Rhode Island at Minnesota, Peacock
12:00 PM Merrimack at UConn, WSFB-3 / WWAX / UConn+
2:00 PM Tennessee Tech at #1 Georgia, SECN+/ESPN+
3:30 PM Iowa State at #21 Iowa (-2.5), CBS
3:30 PM Baylor at #11 Utah (-14), FOX
3:30 PM South Carolina at Kentucky (-10), ABC
3:30 PM NIU at #5 Notre Dame (-28.5), NBC
3:30 PM South Dakota at Wisconsin, FS1
3:30 PM California at Auburn (-13), ESPN2
3:30 PM Jacksonville State at #22 Louisville (-28), ACCNX
3:30 PM Duquesne at Boston College, ACCNX
3:30 PM UMass at Toledo (-20), ESPN+
4:15 PM Middle Tennessee at #6 Ole Miss (-41), SECN
6:00 PM Florida A&M at #12 Miami, ACCNX
7:00 PM USF at #4 Alabama (-31), ESPN
7:00 PM Virginia at Wake Forest (-1.5), ESPN2
7:00 PM #19 Kansas (-5) at Illinois, FS1
7:00 PM Buffalo at #9 Missouri (-34.5), SECN+/ESPN+
7:30 PM #14 Tennessee (-8) vs #24 NC State in Charlotte, ABC
7:30 PM Colorado at Nebraska (-7.5), NBC
7:30 PM Western Michigan at #2 Ohio State (-38), BTN
7:30 PM Nicholls at #18 LSU, SECN+/ESPN+
7:45 PM Houston at #15 Oklahoma (-30), SECN
8:00 PM Appalachian State at #25 Clemson (-17.5), ACCN
10:00 PM Texas Tech at Washington State (-2), FOX
10:00 PM Boise State at #7 Oregon (-19.5), Peacock
10:00 PM Northern Arizona at #20 Arizona, ESPN+
10:15 PM Liberty (-22.5) at New Mexico State, ESPN2
10:30 PM Mississippi State at Arizona State (-6.5), ESPN
10:30 PM Oregon State (-6) at San Diego State, CBSSN
11:00 PM Utah State at #13 USC (-28.5), BTN
Friday, September 6
7:00 PM BYU at SMU (-10.5), ESPN2
7:00 PM Western Illinois at Indiana, BTN
9:00 PM Duke at Northwestern (-2.5), FS1
Saturday, September 7
12:00 PM #3 Texas (-7.5) at #10 Michigan, FOX
12:00 PM Arkansas at #16 Oklahoma State (-7.5), ABC
12:00 PM #17 Kansas State (-10) at Tulane, ESPN
12:00 PM Pitt at Cincinnati (-2), ESPN2
12:00 PM #23 Georgia Tech (-3) at Syracuse, ACCN
12:00 PM Bowling Green at #8 Penn State (-34.5), BTN
12:00 PM Rhode Island at Minnesota, Peacock
12:00 PM Merrimack at UConn, WSFB-3 / WWAX / UConn+
2:00 PM Tennessee Tech at #1 Georgia, SECN+/ESPN+
3:30 PM Iowa State at #21 Iowa (-2.5), CBS
3:30 PM Baylor at #11 Utah (-14), FOX
3:30 PM South Carolina at Kentucky (-10), ABC
3:30 PM NIU at #5 Notre Dame (-28.5), NBC
3:30 PM South Dakota at Wisconsin, FS1
3:30 PM California at Auburn (-13), ESPN2
3:30 PM Jacksonville State at #22 Louisville (-28), ACCNX
3:30 PM Duquesne at Boston College, ACCNX
3:30 PM UMass at Toledo (-20), ESPN+
4:15 PM Middle Tennessee at #6 Ole Miss (-41), SECN
6:00 PM Florida A&M at #12 Miami, ACCNX
7:00 PM USF at #4 Alabama (-31), ESPN
7:00 PM Virginia at Wake Forest (-1.5), ESPN2
7:00 PM #19 Kansas (-5) at Illinois, FS1
7:00 PM Buffalo at #9 Missouri (-34.5), SECN+/ESPN+
7:30 PM #14 Tennessee (-8) vs #24 NC State in Charlotte, ABC
7:30 PM Colorado at Nebraska (-7.5), NBC
7:30 PM Western Michigan at #2 Ohio State (-38), BTN
7:30 PM Nicholls at #18 LSU, SECN+/ESPN+
7:45 PM Houston at #15 Oklahoma (-30), SECN
8:00 PM Appalachian State at #25 Clemson (-17.5), ACCN
10:00 PM Texas Tech at Washington State (-2), FOX
10:00 PM Boise State at #7 Oregon (-19.5), Peacock
10:00 PM Northern Arizona at #20 Arizona, ESPN+
10:15 PM Liberty (-22.5) at New Mexico State, ESPN2
10:30 PM Mississippi State at Arizona State (-6.5), ESPN
10:30 PM Oregon State (-6) at San Diego State, CBSSN
11:00 PM Utah State at #13 USC (-28.5), BTN