All Times ET. Lines from ESPN. Not all games listed.
Thursday, September 22
7:30 PM West Virginia (-2.5) at Virginia Tech, ESPN
7:30 PM Coastal Carolina (-3) at Georgia State, ESPN2
8:30 PM Chattanooga at Illinois, BTN
Friday, September 23
7:00 PM Virginia at Syracuse (-10), ESPN
8:00 PM Nevada at Air Force (-24), FS1
9:00 PM Boise State (-15.5) at UTEP, CBSSN
Saturday, September 24
12:00 PM #5 Clemson (-7) at #21 Wake Forest, ABC
12:00 PM Maryland at #4 Michigan (-16.5), FOX
12:00 PM Missouri at Auburn (-7), ESPN
12:00 PM #17 Baylor at Iowa State (-2.5), ESPN2
12:00 PM Duke at Kansas (-9), FS1
12:00 PM TCU (-1.5) at SMU, ESPNU
12:00 PM Kent State at #1 Georgia (-44.5), SECN+/ESPN+
12:00 PM Central Michigan at #14 Penn State (-26), BTN
12:00 PM Rhode Island at #24 Pitt, ACCN
2:00 PM UMass at Temple (-9), ESPN+
3:30 PM #20 Florida at #11 Tennessee (-11), CBS
3:30 PM Notre Dame (-1) at North Carolina, ABC
3:30 PM #22 Texas (-6.5) at Texas Tech, ESPN
3:30 PM Indiana at Cincinnati (-16.5), ESPN2
3:30 PM Middle Tennessee at #25 Miami (-25.5), ACCN
4:00 PM #15 Oregon (-6.5) at Washington State, FOX
4:00 PM Tulsa at #16 Ole Miss (-21), SECN
7:00 PM #10 Arkansas vs. #23 Texas A&M (-2.5) in Arlington TX, ESPN
7:00 PM NIU at #8 Kentucky (-25.5), ESPN2
7:00 PM Iowa (-7.5) at Rutgers, FS1
7:30 PM Wisconsin at #3 Ohio State (-18), ABC
7:30 PM Vanderbilt at #2 Alabama (-40), SECN
7:30 PM UConn at #12 NC State (-38.5), RSN/ESPN3
8:00 PM Kansas State at #6 Oklahoma (-13), FOX
9:30 PM #7 USC (-6.5) at Oregon State, P12N
10:15 PM Wyoming at #19 BYU (-22.5), ESPN2
10:30 PM #13 Utah (-14) at Arizona State, ESPN
10:30 PM Stanford at #18 Washington (-12.5), FS1
Thursday, September 22
7:30 PM West Virginia (-2.5) at Virginia Tech, ESPN
7:30 PM Coastal Carolina (-3) at Georgia State, ESPN2
8:30 PM Chattanooga at Illinois, BTN
Friday, September 23
7:00 PM Virginia at Syracuse (-10), ESPN
8:00 PM Nevada at Air Force (-24), FS1
9:00 PM Boise State (-15.5) at UTEP, CBSSN
Saturday, September 24
12:00 PM #5 Clemson (-7) at #21 Wake Forest, ABC
12:00 PM Maryland at #4 Michigan (-16.5), FOX
12:00 PM Missouri at Auburn (-7), ESPN
12:00 PM #17 Baylor at Iowa State (-2.5), ESPN2
12:00 PM Duke at Kansas (-9), FS1
12:00 PM TCU (-1.5) at SMU, ESPNU
12:00 PM Kent State at #1 Georgia (-44.5), SECN+/ESPN+
12:00 PM Central Michigan at #14 Penn State (-26), BTN
12:00 PM Rhode Island at #24 Pitt, ACCN
2:00 PM UMass at Temple (-9), ESPN+
3:30 PM #20 Florida at #11 Tennessee (-11), CBS
3:30 PM Notre Dame (-1) at North Carolina, ABC
3:30 PM #22 Texas (-6.5) at Texas Tech, ESPN
3:30 PM Indiana at Cincinnati (-16.5), ESPN2
3:30 PM Middle Tennessee at #25 Miami (-25.5), ACCN
4:00 PM #15 Oregon (-6.5) at Washington State, FOX
4:00 PM Tulsa at #16 Ole Miss (-21), SECN
7:00 PM #10 Arkansas vs. #23 Texas A&M (-2.5) in Arlington TX, ESPN
7:00 PM NIU at #8 Kentucky (-25.5), ESPN2
7:00 PM Iowa (-7.5) at Rutgers, FS1
7:30 PM Wisconsin at #3 Ohio State (-18), ABC
7:30 PM Vanderbilt at #2 Alabama (-40), SECN
7:30 PM UConn at #12 NC State (-38.5), RSN/ESPN3
8:00 PM Kansas State at #6 Oklahoma (-13), FOX
9:30 PM #7 USC (-6.5) at Oregon State, P12N
10:15 PM Wyoming at #19 BYU (-22.5), ESPN2
10:30 PM #13 Utah (-14) at Arizona State, ESPN
10:30 PM Stanford at #18 Washington (-12.5), FS1