I'd go one step further. I like how the 49ers match up against the Chiefs and think the line (PICKEM or Chiefs -1) is a pretty fair representation of things.
The Chiefs did a nice job on Henry but their run defense was 29th in the league by DVOA. I think SF has more ways to attack them in the running game than Tennessee did, particularly outside.
I thought the biggest difference between the Ravens and Chiefs games for the Titans was that their D line dominated the former and got beaten pretty badly in the latter. The Chiefs have so many weapons that your only hope is really to beat them up front and disrupt everything from there. SF has the horses to do that in theory.
Since Mahomes has returned, KC has scored 32, 24, 40, 23, 23, 26, 31, 51, and 35 points, for an average of 31.7 points a game. That's really good, but it's not *insanely* good. During that stretch, they've also gained 530, 310, 259, 346, 419, 350, 336, 434, and 404 yards, for an average of 376.4 yards a game. Again, really good, but not insanely good. Take out the two outliers (530, 259) and the average is 371.2.
So their offense is obviously really really good. Definitely elite. But it's not *historically* good. It was much better last year when they averaged 35.3 points a game and 425.6 yards a game. And the Patriots did a pretty nice job on them in the AFCCG (at Arrowhead, no less), holding them to 31 points and 290 yards. This 49er defense is probably better than last year's Patriots' defense. They definitely have a better pass rush. I wouldn't be shocked if KC puts up 40 because they're more than capable of that. But I also wouldn't be shocked if SF held them to like 24ish points. If so, I think SF's offense (which is criminally underrated - they were the #2 scoring and #4 yardage offense in the NFL this year...better rankings than KC's) can absolutely put up 27ish points on KC.
From a football fan perspective, this is about as good and interesting a game as you can get.